Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA9 | Q16790 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | CA3 | P07451 | 1/20 | 0.69 |
| ▸ | CA4 | P22748 | 1/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28187094 | 1.00 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL4576632 | 1.00 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL138896 | 1.00 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL28121724 | 1.00 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL8801033 | 1.00 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL944251 | 0.97 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL3672103 | 0.97 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL30870098 | 0.97 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL1115430 | 0.97 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL11241559 | 0.97 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483657-A | A kind of lobelia chinensis homogeneous polysaccharide and its preparation method and application | BORUI SACCHARIDE BIOTECH CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-110128562-A | A kind of antitumor Psoralen lipopolysaccharides and its extraction separation method and the application in terms of preparing anti-tumor drug | 黄河科技学院 | 2019-08-16 | — | — | CN | claimed |
| CN-106632708-B | Dendrobium devonianum homogeneous polysaccharide isolate and purify and primary structure identification method | 中国农业科学院农产品加工研究所 | 2019-07-30 | — | — | CN | claimed |
| CN-109535277-A | The extraction process and its content assaying method of anaesthetic Radix Rhapontici seu Radix Echinopsis flower polysaccharide | 内蒙古医科大学 | 2019-03-29 | — | — | CN | claimed |
| CN-104922162-B | A kind of Liu Sheng flammulina velutipes albumen composition and preparation method and application | 吉林农业大学 | 2019-02-26 | — | — | CN | claimed |
| CN-109369816-A | The extracting method of sargassum fusifome anti-aging polysaccharide | 浦江县昂宝生物技术有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-108456259-A | Application of the anoectochilus roxburghii polyose in acute alcohol-induced hepatic injury drug | 福建医科大学 | 2018-08-28 | — | — | CN | claimed |
| CN-106496346-B | A kind of isolation and purification method of acanthopanax trifoliatus polysaccharide | 广东药科大学 | 2018-06-05 | — | — | CN | claimed |
| CN-107892725-A | A kind of thizoma curculiginis polysaccharide and its preparation method and application | 广东药科大学 | 2018-04-10 | — | — | CN | claimed |
| CN-105315383-B | Active polysaccharide and its extraction and purification process and application by extraction purification in agaricus bisporus can processing waste water | 闽南师范大学 | 2018-02-23 | — | — | CN | claimed |
| CN-105037447-B | Root of bidentate achyranthes glycopolymers and its production and use | 广东药科大学 | 2018-01-16 | — | — | CN | claimed |
| CN-107540756-A | Blood coagulation promoting privet flower polysaccharide and extraction and separation method and application thereof | 黄河科技学院 | 2018-01-05 | — | — | CN | claimed |
| CN-107236050-A | Glycopolymers and its preparation method and application in scythian lamb rhizome | 广东药科大学 | 2017-10-10 | — | — | CN | claimed |
| CN-107118283-A | Morinda officinalis sugar polymers and its production and use | 广东药科大学 | 2017-09-01 | — | — | CN | claimed |
| CN-105315382-B | Active polysaccharide and its extraction and purification process and application by extraction purification in agaricus bisporus can processing waste water | 闽南师范大学 | 2017-07-07 | — | — | CN | claimed |
| CN-106832030-A | The method that active polysaccharide is extracted from marine alga | 嵊州市派特普科技开发有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-106496346-A | A kind of isolation and purification method of white polysaccharide | 广东药科大学 | 2017-03-15 | — | — | CN | claimed |
| CN-103073650-B | Red stilbene polysaccharide 4 and effective component preparation and application | UNIV LANGZHOU | 2015-01-07 | — | — | CN | claimed |
| CN-113616686-A | Compound fucoidan composition | 绿活(海南)养老管理有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-102417546-A | Extraction method of rose crude polysaccharide | SHANDONG INST LIGHT INDUSTRY | 2012-04-18 | — | — | CN | disclosed |