Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL4576632 | 0.97 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL28121724 | 0.97 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL28187094 | 0.97 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL8801033 | 0.97 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL28096881 | 0.97 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL138896 | 0.97 | TDP1 (0.69) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL11241559 | 0.94 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL30870098 | 0.94 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL1115430 | 0.94 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 | |
| Phenol SCHEMBL3672103 | 0.94 | TDP1 (0.65) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1693022-B1 | Process and cap for the retraction of sulcus | COLTENE/WHALEDENT AG (CH) | 2020-03-11 | — | — | EP | claimed |
| CN-110522683-A | For improving the composition for repairing dermatoglyph | QINGDAO HUAAO MODERN MEDICAL COSMETOLOGY CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-109944077-A | A kind of production technology for removing deodorization with sterilization | 六安市海洋羽毛有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-107558242-A | A kind of anion down feather material and preparation method thereof | 杭州华俊实业有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-107268278-A | A kind of processing technology of eider down | 合肥远科服装设计有限公司 | 2017-10-20 | — | — | CN | claimed |
| CN-105155036-B | The preparation method and gained non-woven fabrics of a kind of functional non-woven fabric | 罗杰 | 2017-07-14 | — | — | CN | claimed |
| CN-105568547-A | Thermal-insulation and antibacterial wallpaper for building | GENG YUNHUA | 2016-05-11 | — | — | CN | claimed |
| CN-104179023-B | A kind of processing technology of tranquilizing and allaying excitement eider down | JIANGSU XINLONG DOWN CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-105332096-A | Preparation method of functional non-woven fabric, and non-woven fabric prepared via preparation method | GENG YUNHUA | 2016-02-17 | — | — | CN | claimed |
| CN-105155036-A | Preparation method of functional non-woven cloth and non-woven cloth | GENG YUNHUA | 2015-12-16 | — | — | CN | claimed |
| US-7549862-B2 | Process for the retraction of sulcus | COLTENE AG (CH) | 2009-06-23 | — | — | US | claimed |
| US-20070160952-A1 | Process for the retraction of sulcus | KOLLEFRATH RALF | 2007-07-12 | — | — | US | claimed |
| CN-1982532-A | Production of efficient feather deodorant | GUANGDONG MARINE UNIV (CN) | 2007-06-20 | — | — | CN | claimed |
| US-20070065770-A1 | Dental kit and method for retracting sulcus | COLTENE/WHALEDENT AG (CH) | 2007-03-22 | — | — | US | claimed |
| WO-2006089857-A1 | PROCESS FOR THE RETRACTION OF SULCUS | COLTENE AG (CH) | 2006-08-31 | — | — | WO | claimed |
| EP-1693022-A2 | Process for the retraction of sulcus | Coltène AG (CH) | 2006-08-23 | — | — | EP | claimed |
| US-20050202367-A1 | Process for the retraction of sulcus | COLTENE AG (CH) | 2005-09-15 | — | — | US | claimed |
| CN-1636543-A | Deodorant compositions containing cyclodextrin odor controlling agents | PROCTER & GAMBLE (US) | 2005-07-13 | — | — | CN | claimed |
| US-20050069838-A1 | Dental kit and method for retracting sulcus | COLTENE/WHALEDENT AG (CH) | 2005-03-31 | — | — | US | claimed |
| CN-1355685-A | Deodorant compositions containing cyclodextrin odor control agents | PROCTER & GAMBLE (US) | 2002-06-26 | — | — | CN | claimed |