Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097075 | 0.88 | CNR1 (0.45) | CNR1CNR2POLBRENGAA | |
| SCHEMBL28097123 | 0.78 | NR4A2 (0.65) | CNR1CNR2MEN1KMT2APOLB | |
| SCHEMBL16264965 | 0.77 | CDC25A (0.57) | CNR1CNR2MEN1KMT2ATP53 | |
| SCHEMBL318745 | 0.76 | CNR1 (0.53) | CNR1CNR2MEN1KMT2ATP53 | |
| SCHEMBL1224223 | 0.76 | TP53 (0.60) | MEN1KMT2ATP53RXFP1 | |
| SCHEMBL9057781 | 0.76 | CNR1 (0.48) | CNR1CNR2MEN1KMT2ATP53 | |
| SCHEMBL10248359 | 0.74 | CNR1 (0.51) | CNR1CNR2MEN1KMT2ATP53 | |
| SCHEMBL14352972 | 0.74 | CREBBP (0.57) | CNR1CNR2MEN1KMT2APOLB | |
| SCHEMBL14352700 | 0.72 | DHFR (0.53) | CNR1CNR2MEN1KMT2AHDAC6 | |
| SCHEMBL1859925 | 0.71 | POLB (0.64) | MEN1KMT2ATP53POLBHDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884675-A | N-substituted indole carboxylic acid derivative and its preparation method and medical use | 中国药科大学 | 2016-08-24 | — | — | CN | disclosed |