Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14352972 | 0.85 | CREBBP (0.57) | LMNAL3MBTL1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28097075 | 0.80 | CNR1 (0.45) | NR4A2GAAALDH1A1TSHRMAPT | |
| SCHEMBL1855462 | 0.79 | NR4A2 (1.00) | NR4A2GAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL28097074 | 0.78 | CNR1 (0.48) | GAAMEN1KMT2ACNR1CNR2 | |
| SCHEMBL6297494 | 0.78 | NR4A2 (0.76) | NR4A2GAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6984456 | 0.77 | NR4A2 (0.78) | NR4A2GAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL31346908 | 0.77 | GAA (0.79) | NR4A2GAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL2804613 | 0.76 | CNR2 (0.57) | SMN1; SMN2CNR1CNR2 | |
| SCHEMBL14352700 | 0.76 | DHFR (0.53) | GAALMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL9540638 | 0.76 | NR4A2 (0.72) | NR4A2GAALMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884675-A | N-substituted indole carboxylic acid derivative and its preparation method and medical use | 中国药科大学 | 2016-08-24 | — | — | CN | disclosed |