Acrylamide

Acrylamide

SCHEMBL28097172

C=C(NC(C)=O)C(=O)O.C=CC(N)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
FGFR4 P22455 1/20 0.46
CRBN Q96SW2 1/20 0.41
TAS2R38 P59533 1/20 0.38
TDP1 Q9NUW8 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346338 0.84
Methyl Alcohol SCHEMBL8740635 0.82 CRBN (0.39) ALDH1A1CRBNTAS2R38TDP1
Methacrylic Acid SCHEMBL1173108 0.77 ALDH1A1 (0.61) ALDH1A1TSHRFGFR4TDP1ALOX15
Methacrylic Acid SCHEMBL8597277 0.77 ALDH1A1 (0.61) ALDH1A1TSHRFGFR4TDP1ALOX15
Methacrylic Acid SCHEMBL6231225 0.77 ALDH1A1 (0.61) ALDH1A1TSHRFGFR4TDP1ALOX15
Glycine SCHEMBL8303383 0.77 GLRA1 (0.43) CRBNTAS2R38ALOX15HSD17B10
Acrylamide SCHEMBL6130981 0.76 TSHR (0.52) ALDH1A1TSHRFGFR4CRBNTAS2R38
SCHEMBL15080651 0.76 CRBN (0.35) CRBNTAS2R38
Methacrylic Acid SCHEMBL15485306 0.75 ALDH1A1 (0.58) ALDH1A1TSHRFGFR4TDP1ALOX15
Methacrylic Acid SCHEMBL6009531 0.75 ALDH1A1 (0.58) ALDH1A1TSHRFGFR4TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104813222-B Optical film LG化学株式会社 2017-07-18 CN disclosed
CN-104822801-B Liquid-crystal composition LG化学株式会社 2016-09-14 CN disclosed