Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933604 | 0.84 | ALDH1A1 (0.53) | GAAALDH1A1MEN1MAPTTHRB | |
| SCHEMBL8430640 | 0.84 | ALDH1A1 (0.53) | GAAALDH1A1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL6079187 | 0.80 | GAA (0.43) | GAANPC1ALDH1A1MEN1MAPT | |
| SCHEMBL6189730 | 0.80 | ALDH1A1 (0.43) | GAANPC1ALDH1A1MEN1MAPT | |
| SCHEMBL30261672 | 0.80 | GAA (0.43) | GAANPC1ALDH1A1MEN1MAPT | |
| SCHEMBL202933 | 0.80 | ALDH1A1 (0.43) | GAANPC1ALDH1A1MEN1MAPT | |
| SCHEMBL17000445 | 0.80 | CYP3A4 (0.44) | GAANPC1ALDH1A1THRBKDM4E | |
| SCHEMBL31069486 | 0.77 | GAA (0.41) | GAANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL20523636 | 0.77 | GAA (0.41) | GAANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL22588510 | 0.77 | GAA (0.41) | GAANPC1ALDH1A1KDM4ETUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105949069-A | Method for continuous hydrogenation production of 4-chloro-2,5-dimethoxyaniline | 济南和润化工科技有限公司 | 2016-09-21 | — | — | CN | disclosed |