Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20523636 | 1.00 | GAA (0.41) | GAANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL442742 | 0.84 | ALDH1A1 (0.44) | GAAALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL17000445 | 0.78 | CYP3A4 (0.44) | GAANPC1ALDH1A1KDM4ETUBB4A | |
| SCHEMBL30261672 | 0.78 | GAA (0.43) | GAANPC1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6079187 | 0.78 | GAA (0.43) | GAANPC1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5946205 | 0.78 | HSD17B10 (0.50) | ALDH1A1POLBL3MBTL1HSD17B10APP | |
| SCHEMBL28097249 | 0.77 | GAA (0.42) | GAANPC1ALDH1A1KDM4ETUBB4A | |
| SCHEMBL30874274 | 0.77 | POLB (0.48) | GAAALDH1A1POLBL3MBTL1TUBB4A | |
| SCHEMBL20523468 | 0.77 | POLB (0.48) | GAAALDH1A1POLBL3MBTL1TUBB4A | |
| SCHEMBL931631 | 0.77 | POLB (0.44) | GAAALDH1A1KDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546107-A | 2-Thiazole aminophenol derivatives and application thereof | 中国药科大学 | 2024-08-27 | — | — | CN | disclosed |