Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7123362 | 0.88 | MEN1 (0.56) | TSHRHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31520156 | 0.85 | TSHR (0.70) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL30740936 | 0.85 | TSHR (0.70) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL1134614 | 0.83 | TSHR (0.72) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL10672750 | 0.81 | TPMT (0.55) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL1204414 | 0.80 | HTT (0.72) | TSHRAPOBEC3AHTTAPOBEC3GTNFRSF1A | |
| SCHEMBL30740894 | 0.80 | HTT (0.72) | TSHRAPOBEC3AHTTAPOBEC3GTNFRSF1A | |
| SCHEMBL8430188 | 0.79 | TSHR (0.66) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL8148063 | 0.79 | MEN1 (0.61) | TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2 | |
| SCHEMBL985701 | 0.78 | TSHR (0.70) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278941-A | Nine kinds of PTP1B inhibitor and synthesis thereof and application | 南通中国科学院海洋研究所海洋科学与技术研究发展中心 | 2017-01-04 | — | — | CN | claimed |