SCHEMBL30740936

SCHEMBL30740936

COC(=O)c1cc(Br)c(OC)c(OC)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
APOBEC3A P31941 1/20 0.70
HTT P42858 1/20 0.70
APOBEC3G Q9HC16 1/20 0.70
SMN1; SMN2 Q16637 4/20 0.56
HPGD P15428 3/20 0.56
LMNA P02545 2/20 0.56
TNFRSF1A P19438 1/20 0.54
PTPN1 P18031 2/20 0.53
TPMT P51580 2/20 0.53
NCOA1 Q15788 1/20 0.53
NCOA3 Q9Y6Q9 1/20 0.53
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
ALDH1A1 P00352 3/20 0.50
RAB9A P51151 1/20 0.50
CYP3A4 P08684 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPK1 P28482 2/20 0.49
KDM4E B2RXH2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31520156 1.00 TSHR (0.70) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL3349066 0.89 TPMT (0.59) TSHRAPOBEC3AHTTAPOBEC3GHPGD
Methyl Syringate SCHEMBL211747 0.87 MEN1 (0.61) TSHRSMN1; SMN2TPMTMAPTALDH1A1
SCHEMBL28097333 0.85 TSHR (0.64) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL10205503 0.84 SMN1; SMN2 (0.53) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL1134614 0.84 TSHR (0.72) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL30740894 0.84 HTT (0.72) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL1204414 0.84 HTT (0.72) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL985701 0.82 TSHR (0.70) TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2
SCHEMBL20604724 0.82 PTPN1 (0.62) TSHRAPOBEC3AHTTAPOBEC3GLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 TSHR 416/4885APOBEC3A 3334/4885HTT 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.