SCHEMBL7123362

SCHEMBL7123362

COc1cc(C(=O)OC(C)=O)cc(OC)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.51
TSHR P16473 1/20 0.51
MAPT P10636 4/20 0.50
SLC29A1 Q99808 2/20 0.50
TUBB4A P04350 2/20 0.50
TUBB P07437 2/20 0.50
TUBA3C P0DPH7 2/20 0.50
TUBA1B P68363 2/20 0.50
TUBA4A P68366 2/20 0.50
TUBB4B P68371 2/20 0.50
TUBB3 Q13509 2/20 0.50
TUBB2A Q13885 2/20 0.50
TUBB8 Q3ZCM7 2/20 0.50
TUBA3E Q6PEY2 2/20 0.50
TUBA1A Q71U36 2/20 0.50
TUBA1C Q9BQE3 2/20 0.50
TUBB6 Q9BUF5 2/20 0.50
TUBB2B Q9BVA1 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8148063 0.90 MEN1 (0.61) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL28097333 0.88 TSHR (0.64) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL27578914 0.85 LMNA (0.66) MEN1KMT2ATSHRHTTLMNA
SCHEMBL10887444 0.83 MEN1 (0.54) MEN1KMT2ASMN1; SMN2TSHRMAPT
Methyl Syringate SCHEMBL211747 0.82 MEN1 (0.61) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL6559151 0.81 MAPT (0.59) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL10876059 0.81 ABCG2 (0.53) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL28469235 0.81 MEN1 (0.61) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL6939779 0.81 KDM4E (0.40) MEN1KMT2ASMN1; SMN2TSHRTPMT
SCHEMBL8148066 0.80 TSHR (0.59) MEN1KMT2ASMN1; SMN2TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030008914-A1 PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS MILLENNIUM PHARMACEUTICALS, INC. 2003-01-09 US disclosed
EP-1123095-A1 PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS Millennium Pharmaceuticals, Inc. (US) 2001-08-16 EP disclosed
WO-2000023071-A9 PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS LEUKOSITE INC (US) 2000-09-14 WO disclosed
WO-2000023071-A1 PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS LEUKOSITE, INC. (US) 2000-04-27 WO disclosed
CN-1142495-A Platelet activating factor antagonist and preparation thereof MILLITARY MEDICAL UNIV NO 2 P (CN) 1997-02-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008914-A1 PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS ALOX5, ALOX5AP, ALOX15 MEN1 4464/4885KMT2A 2343/4885SMN1; SMN2 4553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.