Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 3/20 | 0.35 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.35 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL25389207 | 0.87 | CES1 (0.38) | TSHRHRH4HRH3L3MBTL1CES1 | |
| Trifluoroacetic Acid SCHEMBL9068482 | 0.87 | NAPRT (0.50) | TSHRNAPRTTDP1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL16824180 | 0.87 | NAPRT (0.50) | TSHRNAPRTTDP1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL158703 | 0.87 | NAPRT (0.50) | TSHRNAPRTTDP1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30798243 | 0.87 | CES1 (0.38) | TSHRHRH4HRH3L3MBTL1CES1 | |
| Trifluoroacetic Acid SCHEMBL6076010 | 0.84 | NAPRT (0.47) | TSHRNAPRTTDP1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL27559395 | 0.84 | NAPRT (0.47) | TSHRNAPRTTDP1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL4067637 | 0.82 | ALDH1A1 (0.48) | TSHRNAPRTTDP1HRH4HRH3 | |
| Pyridine SCHEMBL28142784 | 0.82 | NAPRT (0.45) | TSHRNAPRTTDP1PLOD2PLOD3 | |
| Pyridine SCHEMBL27565948 | 0.81 | NAPRT (0.39) | TSHRNAPRTTDP1PLOD2PLOD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843903-A | CYCLIC DINUCLEOTIDE COMPOUNDS | 勃林格殷格翰国际有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-106459131-B | Cyclic annular dinucleotides as STING regulator | 葛兰素史克知识产权开发有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109451740-A | For treating the cyclic annular dinucleotides of illness such as cancer relevant to STING activity | 先天肿瘤免疫公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-106459131-A | Cyclic di-nucleotides as modulators of STING | 葛兰素史克知识产权开发有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104151384-B | One prepares N6the improved method of-benzoyl-D-adenosine | 济南尚博生物科技有限公司 | 2016-09-28 | — | — | CN | disclosed |