Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9068482

O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 5/20 0.40
PLOD2 O00469 2/20 0.38
PLOD3 O60568 2/20 0.38
PLOD1 Q02809 2/20 0.38
UBE2N P61088 1/20 0.37
CES1 P23141 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.34
APP P05067 1/20 0.34
GAA P10253 1/20 0.34
HCAR3 P49019 1/20 0.34
HCAR2 Q8TDS4 1/20 0.34
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
KDM1A O60341 1/20 0.34
CDK5 Q00535 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL16824180 1.00 NAPRT (0.50) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL158703 1.00 NAPRT (0.50) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL6076010 0.97 NAPRT (0.47) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL27559395 0.97 NAPRT (0.47) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL5528548 0.93 NAPRT (0.43) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL28316548 0.91 TSHR (0.41) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL8138931 0.88 PLOD2 (0.40) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL28097336 0.87 TSHR (0.38) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoroacetic Acid SCHEMBL28325627 0.87 TSHR (0.38) NAPRTTSHRTDP1L3MBTL1PLOD2
Trifluoromethanesulfonic Acid SCHEMBL27353707 0.87 L3MBTL1 (0.43) NAPRTTSHRTDP1L3MBTL1PLOD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
CN-110167937-B Bicyclic bis-heteroaryl derivatives as modulators of protein aggregation UCB生物制药私人有限公司 2022-03-29 CN disclosed
WO-2015095492-A1 TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS INCYTE CORPORATION (US) 2015-06-25 WO disclosed
US-5481029-A Process for preparation of ketones SOLVAY FLUOR UND DERIVATE GMBH (DE) 1996-01-02 US disclosed