Phosphoric Acid

Phosphoric Acid

SCHEMBL28097386

C=C.C=CCOCC=C.O.O.O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 1/20 0.37
LPAR2 Q9HBW0 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34
CA9 Q16790 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.30
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27451943 0.97 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL5090654 0.97 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL29820 0.95 ALDH1A1 (0.41) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL27925652 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL27878548 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL1478991 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL17187059 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL17187057 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL26133950 0.87 ALDH1A1 (0.37) ALDH1A1CA1CA2CA7LPAR2
Phosphoric Acid SCHEMBL28199777 0.85 CA1 (0.35) ALDH1A1CA1CA2CA7LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106046303-A Polyol composition for producing flexible polyurethane foam and flexible polyurethane foam 东洋橡胶工业株式会社 2016-10-26 CN disclosed