Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568104 | 0.77 | ERBB2 (0.49) | TNK2MAOASCN9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL23701631 | 0.76 | ADORA2A (0.42) | ALDH1A1 | |
| SCHEMBL28203856 | 0.75 | NCOA1 (0.46) | MAOASMN1; SMN2 | |
| SCHEMBL15519110 | 0.74 | PIK3CD (0.48) | TNK2BTK | |
| SCHEMBL29611096 | 0.74 | PIK3CD (0.48) | TNK2BTK | |
| SCHEMBL30127396 | 0.73 | MAOA (0.54) | MAOBMAOAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16792619 | 0.73 | MAOA (0.54) | MAOBMAOAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL31375095 | 0.71 | TNK2 (0.43) | TNK2MAOBMAOASCN9AFEN1 | |
| SCHEMBL19353387 | 0.71 | PIM1 (0.41) | TNK2MAOBMAOAFEN1MAPT | |
| SCHEMBL6003624 | 0.71 | ALDH1A1 (0.40) | TNK2MAOAMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103534258-B | Tyrosine kinase inhibitor | 普林斯匹亚生物制药公司 | 2016-09-14 | — | — | CN | disclosed |