Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868173 | 0.86 | L3MBTL1 (0.38) | ALDH1A1CYP1A2KDM4EHPGDHSD17B10 | |
| SCHEMBL28122101 | 0.85 | HAAO (0.38) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL2258690 | 0.85 | HAAO (0.40) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL18280372 | 0.83 | HAAO (0.39) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL3000590 | 0.83 | GABRP (0.40) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL1963804 | 0.80 | TSHR (0.40) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL23703865 | 0.79 | HAAO (0.39) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL8072439 | 0.79 | RARB (0.36) | HAAOALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL7649724 | 0.79 | GABRP (0.46) | ALDH1A1CYP1A2KDM4EHPGDHSD17B10 | |
| SCHEMBL11870875 | 0.79 | PTGS1 (0.39) | HAAOALDH1A1CYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939437-A | AMIDE COMPOUNDS AS NEUROPEPTIDES AS APPETITE REGULATORS, ANXIOLYTIC ACTIVITY AND ANTICARCINOGENIC AGENTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |
| WO-1995030647-A1 | CCK AND GASTRIN RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |