SCHEMBL2809781

SCHEMBL2809781

CC/C(=C\Oc1cccc(C)c1)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
ACHE P22303 1/20 0.42
GAA P10253 2/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HPGD P15428 1/20 0.40
POLB P06746 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 3/20 0.39
FAAH O00519 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2809783 1.00 LMNA (0.44) LMNAACHEGAAKMT2ATDP1
SCHEMBL2813061 0.85 LMNA (0.46) LMNAACHEGAAKMT2ATDP1
SCHEMBL2813058 0.85 LMNA (0.46) LMNAACHEGAAKMT2ATDP1
SCHEMBL2813105 0.83 RECQL (0.40) KMT2ATDP1L3MBTL1HPGDSMN1; SMN2
SCHEMBL2813106 0.83 RECQL (0.40) KMT2ATDP1L3MBTL1HPGDSMN1; SMN2
SCHEMBL2811889 0.82 MAPT (0.41) LMNAGAAKMT2ATDP1L3MBTL1
SCHEMBL2811892 0.82 MAPT (0.41) LMNAGAAKMT2ATDP1L3MBTL1
SCHEMBL2808634 0.80 HTT (0.50) LMNAKMT2AL3MBTL1POLBSMN1; SMN2
SCHEMBL2811132 0.80 POLB (0.46) LMNAGAAKMT2AL3MBTL1POLB
SCHEMBL2808632 0.80 HTT (0.50) LMNAKMT2AL3MBTL1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 LMNA 2201/4885ACHE 49/4885GAA 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.