SCHEMBL2811889

SCHEMBL2811889

CC/C(=C\Oc1ccc(C)cc1)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
DHODH Q02127 1/20 0.39
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
GAA P10253 2/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
MMP13 P45452 1/20 0.36
TP53 P04637 1/20 0.35
THRB P10828 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811892 1.00 MAPT (0.41) MAPTKDM4EALDH1A1DHODHLMNA
SCHEMBL2809198 0.89 GSK3B (0.44) KMT2ANPC1SMN1; SMN2HTTRAB9A
SCHEMBL2809196 0.89 GSK3B (0.44) KMT2ANPC1SMN1; SMN2HTTRAB9A
SCHEMBL2813105 0.85 RECQL (0.40) MAPTKDM4ETDP1MEN1HPGD
SCHEMBL2813106 0.85 RECQL (0.40) MAPTKDM4ETDP1MEN1HPGD
SCHEMBL2811324 0.83 L3MBTL1 (0.42) MAPTALDH1A1LMNAMEN1HPGD
SCHEMBL2811323 0.83 L3MBTL1 (0.42) MAPTALDH1A1LMNAMEN1HPGD
SCHEMBL2809783 0.82 LMNA (0.44) MAPTALDH1A1LMNATDP1HPGD
SCHEMBL2809781 0.82 LMNA (0.44) MAPTALDH1A1LMNATDP1HPGD
SCHEMBL2813615 0.80 NPC1 (0.45) MAPTKDM4EALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 MAPT 4608/4885KDM4E 3990/4885ALDH1A1 405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.