Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509781 | 0.80 | KLK7 (0.44) | TYK2JAK2CYP3A4JAK1TAS1R3 | |
| SCHEMBL16677947 | 0.78 | ELANE (0.57) | TAS1R3TAS1R1TAS1R2KMT2AGAA | |
| SCHEMBL6679298 | 0.78 | KMT2A (0.49) | CYP3A4KMT2AMAPTITGB1ITGA4 | |
| SCHEMBL6509892 | 0.78 | CNR2 (0.46) | KMT2AMAPTITGB1ITGA4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6514192 | 0.77 | TYK2 (0.51) | TYK2JAK2CYP3A4JAK1TAS1R3 | |
| SCHEMBL7384072 | 0.76 | TYK2 (0.65) | TYK2JAK2CYP3A4JAK1TAS1R3 | |
| SCHEMBL4154853 | 0.73 | TYK2 (0.71) | TYK2JAK2CYP3A4JAK1TAS1R3 | |
| SCHEMBL25219057 | 0.73 | TYK2 (0.66) | TYK2TAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL16677858 | 0.73 | LMNA (0.56) | CYP3A4KMT2AGAAMAPTRAB9A | |
| SCHEMBL16675163 | 0.73 | LMNA (0.60) | CYP3A4KMT2AGAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104023751-B | Targeted delivery extremely expresses the integrin antagonists conjugate of the cell of VLA-4 | 弗·哈夫曼-拉罗切有限公司 | 2016-11-09 | — | — | CN | disclosed |