Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679298 | 0.81 | KMT2A (0.49) | KMT2AITGB1ITGA4MEN1ITGA2 | |
| SCHEMBL28097863 | 0.80 | TYK2 (0.52) | KMT2AITGB1ITGA4MEN1ITGA2 | |
| SCHEMBL6509892 | 0.76 | CNR2 (0.46) | KMT2AITGB1ITGA4ALDH1A1 | |
| SCHEMBL9203029 | 0.70 | KMT2A (0.55) | KLK7KMT2APOLBMEN1L3MBTL1 | |
| SCHEMBL4154853 | 0.70 | TYK2 (0.71) | KMT2APOLBMEN1TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL6514192 | 0.69 | TYK2 (0.51) | KMT2AITGB1ITGA4POLBMEN1 | |
| SCHEMBL7563566 | 0.69 | MAPT (0.46) | ITGB1ITGA4MAPK1ALDH1A1GAA | |
| SCHEMBL16583378 | 0.69 | PTGS2 (0.47) | KMT2AITGB1ITGA4POLBMEN1 | |
| SCHEMBL2841085 | 0.67 | HDAC4 (0.47) | KMT2AITGB1ITGA4POLBMEN1 | |
| SCHEMBL12020093 | 0.67 | MAPT (0.48) | KMT2AITGB1ITGA4POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911451-B1 | Phenylalanine derivatives | CELLTECH R&D LIMITED (GB) | 2005-06-28 | — | — | US | disclosed |