Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17298013 | 0.84 | TNKS2 (0.62) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL24807018 | 0.83 | POLB (0.51) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL6929589 | 0.82 | KDM4E (0.65) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL29900514 | 0.82 | KDM4E (0.65) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL28097943 | 0.81 | POLB (0.56) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL19104694 | 0.80 | LMNA (0.54) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL2261181 | 0.79 | TNKS2 (0.69) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL7366882 | 0.79 | PKM (0.59) | PIM1PIM2TDP1GAAALDH1A1 | |
| SCHEMBL24807720 | 0.78 | LMNA (0.50) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL1891979 | 0.76 | LMNA (0.56) | POLBLMNAKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045922-A | 2-(Amino) methylquinazolin-4(3H)-one compound and preparation method and application thereof | 湘潭大学 | 2016-10-26 | — | — | CN | claimed |
| CN-106045922-A | 2-(Amino) methylquinazolin-4(3H)-one compound and preparation method and application thereof | 湘潭大学 | 2016-10-26 | — | — | CN | disclosed |