Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22428829 | 0.86 | HTR7 (0.47) | PDE4ATSHRNPC1RAB9AKMT2A | |
| SCHEMBL29363167 | 0.86 | HTR7 (0.47) | PDE4ATSHRNPC1RAB9AKMT2A | |
| SCHEMBL29870758 | 0.83 | KMT2A (0.44) | PDE4AMAPTMGLLALDH1A1HTT | |
| SCHEMBL23904838 | 0.82 | CA12 (0.46) | PDE4AMAPTALDH1A1HPGDHTT | |
| SCHEMBL1223701 | 0.81 | PDE4A (0.47) | PDE4AMAPTALDH1A1HTTLMNA | |
| SCHEMBL30419944 | 0.80 | PARP1 (0.50) | PDE4AMAPTMGLLALDH1A1HTT | |
| SCHEMBL27976330 | 0.80 | KMT2A (0.52) | MAPTALDH1A1HPGDHTTLMNA | |
| SCHEMBL17442599 | 0.79 | ALOX15 (0.58) | MAPTALDH1A1HTTALOX15L3MBTL1 | |
| SCHEMBL24735857 | 0.78 | HSP90AA1 (0.60) | PDE4AMAPTALDH1A1HTTLMNA | |
| SCHEMBL24421991 | 0.78 | SMN1; SMN2 (0.51) | MAPTALDH1A1HPGDTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105968115-A | Quinoline compounds and preparation method thereof, and intermediate, pharmaceutical composition and application of quinoline compounds | 上海医药集团股份有限公司 | 2016-09-28 | — | — | CN | disclosed |