SCHEMBL28098355

SCHEMBL28098355

[CH]=C(c1cc[nH]n1)N1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
POLB P06746 2/20 0.34
HPGD P15428 6/20 0.33
KDM5A P29375 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
KDM5B Q9UGL1 1/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 3/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALPL P05186 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
GNE Q9Y223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15313374 0.79 HPGD (0.50) ALDH1A1POLBHPGDKDM5AKDM4C
SCHEMBL3308470 0.76 GNE (0.49) ALDH1A1POLBHPGDRAB9ASMN1; SMN2
SCHEMBL5162423 0.72 RAB9A (0.42) ALDH1A1POLBHPGDRAB9ASMN1; SMN2
SCHEMBL28193968 0.70 GAA (0.33) ALDH1A1HPGDRAB9ANPC1MAPT
SCHEMBL5162764 0.70 RAB9A (0.40) ALDH1A1POLBHPGDRAB9ASMN1; SMN2
SCHEMBL28251927 0.69 GAA (0.32) ALDH1A1HPGDRAB9ANPC1MAPT
SCHEMBL1574233 0.68 HTT (0.50) POLB
SCHEMBL21855955 0.68 ALDH1A1 (0.47) ALDH1A1POLBHPGDSMN1; SMN2NPC1
SCHEMBL5592523 0.68 HTT (0.36)
Hydrochloric Acid SCHEMBL4597452 0.67 HTT (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106061945-A Two-photon-absorbing compound 大塚电子株式会社 2016-10-26 CN disclosed