Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | ADH5 | P11766 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991476 | 0.87 | AKR1C3 (0.50) | MAPTSMN1; SMN2L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL17133900 | 0.83 | AKR1C3 (0.60) | MAPTSMN1; SMN2AKR1C3AKR1C2RORC | |
| SCHEMBL402398 | 0.83 | ADH5 (0.58) | AKR1C3AKR1C2SRD5A2S1PR1FFAR2 | |
| SCHEMBL27702486 | 0.83 | AKR1C3 (0.50) | L3MBTL1AKR1C3AKR1C2RORCSRD5A2 | |
| SCHEMBL27741048 | 0.82 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL27724772 | 0.82 | PDK2 (0.51) | MAPTAKR1C3AKR1C2SRD5A2S1PR1 | |
| SCHEMBL403135 | 0.80 | AKR1C3 (0.55) | AKR1C3AKR1C2SRD5A2S1PR1FFAR2 | |
| SCHEMBL9517508 | 0.80 | MAPT (0.59) | MAPTSMN1; SMN2L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL3903631 | 0.79 | EGFR (0.57) | AKR1C3AKR1C2SRD5A2S1PR1 | |
| SCHEMBL28192342 | 0.79 | PLK1 (0.57) | AKR1C3AKR1C2RORCS1PR1FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822666-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-09-21 | — | — | CN | disclosed |