Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870990 | 0.83 | CYP17A1 (0.50) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL9609808 | 0.80 | SMN1; SMN2 (0.82) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL16144656 | 0.79 | MAPT (0.62) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL16234657 | 0.79 | MAPT (0.44) | SMN1; SMN2MAPTHPGDCA12CA1 | |
| SCHEMBL12421799 | 0.79 | POLB (0.58) | SMN1; SMN2MAPTHPGDCA12CA1 | |
| SCHEMBL18600372 | 0.77 | CYP1A2 (0.48) | SMN1; SMN2MAPTHPGDCA12CA1 | |
| SCHEMBL7251623 | 0.74 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL432166 | 0.74 | CA1 (0.51) | SMN1; SMN2MAPTCA12CA1CA2 | |
| SCHEMBL4817527 | 0.74 | MAPT (0.51) | SMN1; SMN2MAPTCA12CA1CA2 | |
| SCHEMBL4226357 | 0.73 | GAA (0.63) | SMN1; SMN2MAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960402-B | Microbicidal heterobicyclic derivatives | 先正达参股股份有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-105960402-A | Microbicidal heterobicyclic derivatives | 先正达参股股份有限公司 | 2016-09-21 | — | — | CN | disclosed |