Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 12/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239110 | 0.80 | ALDH1A1 (0.64) | EPAS1POLBLMNAKMT2ATSHR | |
| SCHEMBL34475121 | 0.80 | EPAS1 (0.47) | EPAS1POLBLMNAKMT2ATSHR | |
| SCHEMBL16560895 | 0.79 | EPAS1 (1.00) | EPAS1 | |
| SCHEMBL6687404 | 0.79 | MCOLN3 (0.58) | POLBMCOLN3LMNAKDM4EPKM | |
| SCHEMBL2590043 | 0.79 | SMN1; SMN2 (0.65) | EPAS1POLBMCOLN3LMNAKDM4E | |
| SCHEMBL16555959 | 0.78 | EPAS1 (0.71) | EPAS1 | |
| SCHEMBL30856819 | 0.78 | EPAS1 (0.71) | EPAS1 | |
| SCHEMBL9116477 | 0.78 | PTGS2 (0.57) | EPAS1POLBMCOLN3LMNAKDM4E | |
| SCHEMBL4201928 | 0.78 | SMN1; SMN2 (0.50) | EPAS1POLBKMT2ATSHR | |
| SCHEMBL24456745 | 0.77 | EPAS1 (0.59) | EPAS1POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985266-A | Trifluoromethylthiolation reagent, and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2016-10-05 | — | — | CN | disclosed |