Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918724 | 0.87 | — | — | |
| SCHEMBL424656 | 0.87 | — | — | |
| Formaldehyde SCHEMBL28529287 | 0.85 | TDO2 (0.41) | TDO2KCNQ3KCNQ2HDAC1HDAC6 | |
| SCHEMBL30058277 | 0.84 | — | — | |
| Acetic Acid SCHEMBL29276427 | 0.83 | HDAC1 (0.44) | TDO2KCNQ3KCNQ2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL25293542 | 0.82 | TDO2 (0.42) | TDO2KCNQ3KCNQ2HDAC1HDAC6 | |
| Formic Acid SCHEMBL27887998 | 0.77 | HDAC1 (0.41) | HDAC1HDAC6SMN1; SMN2ADRA2AADRA2B | |
| SCHEMBL13750539 | 0.76 | TDO2 (0.46) | TDO2NPC1PTGS2MAPTGRM5 | |
| Formic Acid SCHEMBL28805131 | 0.75 | ADRA2A (0.41) | HDAC1HDAC6SMN1; SMN2PTGS2ADRA2A | |
| Formic Acid SCHEMBL31273542 | 0.75 | KDM4E (0.46) | HDAC1HDAC6ALDH1A1SMN1; SMN2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119255988-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118339151-A | Compound for inhibiting or degrading BRD9, composition and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117881678-A | Compound with SHP2 protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117836299-A | Novel bifunctional heterocyclic compounds with Bruton tyrosine kinase decomposition via ubiquitin proteasome pathway and uses thereof | 韩国化学研究院 | 2024-04-05 | — | — | CN | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116354961-A | Somatostatin receptor 5 antagonist, and pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-06-30 | — | — | CN | disclosed |
| CN-116157390-A | Compounds for androgen receptor degradation and pharmaceutical uses thereof | 尤比克斯治疗公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-106459006-A | 2,2,2-trifluoroethyl-thiadiazines | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105960405-A | glutaminase inhibitors | 理森制药股份公司 | 2016-09-21 | — | — | CN | disclosed |