Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.77 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL4626241 | 0.97 | DNM1 (0.81) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL28952238 | 0.97 | DNM1 (0.81) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL28115805 | 0.94 | DNM1 (0.77) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Hexadecylamine SCHEMBL27994989 | 0.94 | DNM1 (0.82) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Hexadecylamine SCHEMBL28025404 | 0.94 | DNM1 (0.82) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL28084984 | 0.94 | DNM1 (0.77) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL6239869 | 0.92 | DNM1 (0.72) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL21359732 | 0.92 | DNM1 (0.78) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL28084983 | 0.92 | DNM1 (0.72) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL28175845 | 0.92 | DNM1 (0.78) | DNM1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934459-A | Curable resin having excellent flexibility after curing, (meth) acryloyl curable resin, and liquid crystal sealing composition | 协立化学产业株式会社 | 2016-09-07 | — | — | CN | disclosed |