SCHEMBL28099455

SCHEMBL28099455

C[N+](C)(C)C(Cc1c[nH]c(=S)[nH]1)C(=O)[O-].N[C@@H](Cc1cnc(S)[nH]1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC22A4 Q9H015 1/20 0.64
CYP3A4 P08684 1/20 0.36
SLC7A5 Q01650 1/20 0.36
POLB P06746 2/20 0.34
ALPL P05186 1/20 0.34
ALPG P10696 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188140 0.81 SLC22A4 (0.52) SLC22A4POLBALPLALPGGAA
SCHEMBL2954946 0.81 SLC22A4 (0.52) SLC22A4POLBALPLALPGGAA
Water SCHEMBL7254213 0.80 SLC22A4 (0.51) SLC22A4POLBALPLALPGGAA
SCHEMBL9985141 0.80 SLC22A4 (1.00) SLC22A4POLBALPLALPGGAA
SCHEMBL9986385 0.80 SLC22A4 (1.00) SLC22A4POLBALPLALPGGAA
SCHEMBL2215409 0.80 SLC22A4 (1.00) SLC22A4POLBALPLALPGGAA
SCHEMBL1065163 0.76 SLC7A5 (0.53) CYP3A4SLC7A5POLB
SCHEMBL5284026 0.76 SLC7A5 (0.53) CYP3A4SLC7A5POLB
SCHEMBL14323788 0.76 SLC7A5 (0.53) CYP3A4SLC7A5POLB
SCHEMBL19571061 0.75 SLC22A4 (0.38) SLC22A4POLBALPLALPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105982890-A Use of ergothioneine for activating the Nrf2 signaling pathway of cells 中国医药大学 2016-10-05 CN disclosed