Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579635 | 0.98 | HTR2A (0.45) | HTR2AMAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL88302 | 0.98 | HTR2A (0.45) | HTR2AMAPTKMT2AHDAC3HDAC4 | |
| Hexane SCHEMBL28816063 | 0.89 | BCHE (0.45) | HTR2AKMT2AMEN1 | |
| Piperidine SCHEMBL5679331 | 0.85 | MAPT (0.42) | MAPTKMT2ATSHR | |
| SCHEMBL28246095 | 0.83 | KMT2A (0.44) | KMT2AFABP7FABP5 | |
| SCHEMBL1567087 | 0.83 | HTR2A (0.45) | HTR2AMAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL28338711 | 0.81 | HTR2A (0.48) | HTR2AMAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL21895871 | 0.81 | MTNR1A (0.49) | HTR2AKMT2AHDAC3HDAC4HDAC7 | |
| SCHEMBL27880277 | 0.81 | HTR2A (0.44) | HTR2AMAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL6817705 | 0.80 | CYP1A2 (0.36) | MAPTKMT2ACYP1A2TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103957927-B | Glucagon superfamily peptides exhibiting glucocorticoid receptor activity | 印第安纳大学研究及科技有限公司 | 2016-11-09 | — | — | CN | disclosed |