Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579635 | 0.86 | HTR2A (0.45) | MAPTTSHRKMT2A | |
| SCHEMBL88302 | 0.86 | HTR2A (0.45) | MAPTTSHRKMT2A | |
| Ammonia Solution, Strong SCHEMBL28099493 | 0.85 | HTR2A (0.44) | MAPTTSHRKMT2A | |
| Hexane SCHEMBL28816063 | 0.78 | BCHE (0.45) | KMT2A | |
| SCHEMBL28246095 | 0.73 | KMT2A (0.44) | KMT2A | |
| SCHEMBL1567087 | 0.73 | HTR2A (0.45) | MAPTTSHRKMT2A | |
| SCHEMBL21895871 | 0.72 | MTNR1A (0.49) | KMT2A | |
| SCHEMBL28338711 | 0.72 | HTR2A (0.48) | MAPTTSHRKMT2A | |
| SCHEMBL27880277 | 0.72 | HTR2A (0.44) | MAPTTSHRKMT2A | |
| SCHEMBL6817705 | 0.70 | CYP1A2 (0.36) | MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618095-A2 | PREPARATION OF SUBSTITUTED QUINAZOLINES | Warner-Lambert Company LLC (US) | 2006-01-25 | — | — | EP | disclosed |
| WO-2004069791-A2 | PREPARATION OF SUBSTITUTED QUINAZOLINES | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |