SCHEMBL28099573

SCHEMBL28099573

Clc1cccc(-n2nnc3ccccc32)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.55
TDO2 P48775 1/20 0.55
HPGD P15428 1/20 0.54
FGFR1 P11362 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.50
MPO P05164 1/20 0.48
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GLA P06280 1/20 0.47
THRB P10828 1/20 0.47
RAB9A P51151 1/20 0.46
KCNMA1 Q12791 1/20 0.46
SLC9A1 P19634 1/20 0.46
MAPT P10636 1/20 0.45
ALDH1A1 P00352 2/20 0.45
PTK2 Q05397 2/20 0.45
NT5E P21589 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28980715 0.87 HPGD (0.61) IDO1TDO2HPGDFGFR1MPO
SCHEMBL3977744 0.81 TDP1 (0.56) IDO1TDO2SMN1; SMN2KDM4ENPC1
SCHEMBL28887258 0.80 HPGD (0.49) IDO1TDO2HPGDFGFR1SMN1; SMN2
SCHEMBL241393 0.80 IDO1 (0.54) IDO1TDO2SMN1; SMN2KDM4ENPC1
SCHEMBL16596178 0.80 NT5E (0.58) FGFR1SMN1; SMN2KDM4ENPC1L3MBTL1
SCHEMBL2627246 0.80 KDM4E (0.64) HPGDSMN1; SMN2KDM4ENPC1L3MBTL1
SCHEMBL12204569 0.80 RAB9A (0.56) HPGDSMN1; SMN2KDM4ENPC1L3MBTL1
SCHEMBL165333 0.80 SMN1; SMN2 (0.71) HPGDSMN1; SMN2KDM4ENPC1L3MBTL1
SCHEMBL14944391 0.80 FGFR1 (0.57) HPGDFGFR1SMN1; SMN2KDM4ENPC1
SCHEMBL16728738 0.80 SMN1; SMN2 (0.43) IDO1TDO2SMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105938801-B A kind of method of temporary bonding, composition and structure 罗门哈斯电子材料有限责任公司 2019-09-20 CN disclosed
CN-105938801-A Ephemeral bonding 罗门哈斯电子材料有限责任公司 2016-09-14 CN disclosed