Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 6/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148276 | 0.81 | GSK3B (0.45) | PARP1GSK3BADKWEE1CHEK1 | |
| SCHEMBL135332 | 0.79 | GSK3B (0.56) | PARP1GSK3BADKWEE1CHEK1 | |
| SCHEMBL29710128 | 0.78 | GRM5 (0.46) | PARP1GSK3BWEE1CHEK1MEN1 | |
| SCHEMBL9279015 | 0.78 | GRM5 (0.46) | PARP1GSK3BWEE1CHEK1MEN1 | |
| SCHEMBL27673439 | 0.78 | GSK3B (0.45) | PARP1GSK3BADKWEE1CHEK1 | |
| SCHEMBL6785035 | 0.78 | GSK3B (0.45) | PARP1GSK3BADKWEE1CHEK1 | |
| SCHEMBL28213146 | 0.78 | MAOA (0.46) | PARP1GSK3BADKWEE1CHEK1 | |
| SCHEMBL7686016 | 0.78 | GSK3B (0.45) | PARP1GSK3BADKWEE1CHEK1 | |
| SCHEMBL29032840 | 0.77 | GSK3B (0.54) | PARP1GSK3BADKWEE1CHEK1 | |
| Ammonia Solution, Strong SCHEMBL28821133 | 0.77 | GSK3B (0.54) | PARP1GSK3BADKWEE1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311825-B | Phenolphthalein type copolyimide and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2017-05-17 | — | — | CN | disclosed |
| CN-105985521-A | Polybenzimidazole imide and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2016-10-05 | — | — | CN | disclosed |