SCHEMBL135332

SCHEMBL135332

O=C1NC(=O)c2c1cccc2-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.56
CASP3 P42574 3/20 0.48
CASP2 P42575 1/20 0.48
CASP7 P55210 1/20 0.48
CASP6 P55212 1/20 0.48
CASP8 Q14790 1/20 0.48
PARP1 P09874 2/20 0.47
PTP4A3 O75365 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 2/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
ADK P55263 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PARP11 Q9NR21 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28821133 0.98 GSK3B (0.54) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL29032840 0.98 GSK3B (0.54) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL5616554 0.92 GSK3B (0.52) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL9016868 0.88 GSK3B (0.50) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL8429414 0.87 GSK3B (0.61) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL28839558 0.84 GSK3B (0.44) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL16754925 0.84 GSK3B (0.62) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL28938878 0.83 PTPRC (0.46) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL9116090 0.82 GSK3B (0.45) GSK3BCASP3CASP2CASP7CASP6
SCHEMBL30956736 0.82 CASP3 (0.48) GSK3BCASP3CASP2CASP7CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028857-A1 PROTOPORPHYRINOGEN OXIDASE (PPO) RESISTANCE PLANT PLANTARC BIO LTD. (IL) 2024-02-08 WO claimed
CN-115281188-B Preparation method and application of suspending agent containing water-soluble herbicide 浙江新安化工集团股份有限公司 2023-05-19 CN claimed
WO-2022180626-A1 HERBICIDAL COMPOSITIONS COMPRISING IMIDAZOLINONE-BASED ACETOLACTATE SYNTHASE INHIBITORS AND USES THEREOF ADAMA AGAN LTD. (IL) 2022-09-01 WO claimed
WO-2022115930-A1 SUSPOEMULSION, PROCESS FOR PREPARING A SUSPOEMULSION, METHOD FOR CONTROLLING UNDESIRED VEGETATION AND/OR PESTS AND METHOD FOR TREATING SEEDS SUMITOMO CHEMICAL BRASIL INDÚSTRIA QUÍMICA S.A. (BR) 2022-06-09 WO claimed
EP-3923722-A1 HERBICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2021-12-22 EP claimed
WO-2021064626-A2 HERBICIDE COMPOSITION UPL Corporation Limited (MU) 2021-04-08 WO claimed
WO-2020164922-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO claimed
US-20190315775-A1 MODIFIED PHENYLPHTHALIMIDE AND PHARMACEUTICAL COMPOSITION HAVING SAME AS ACTIVE INGREDIENT KEIO UNIVERSITY (JP) 2019-10-17 US claimed
CN-110325038-A The mixture of beflubutamid or its optically-active enriched form and second herbicidal agent FMC公司 2019-10-11 CN claimed
EP-3530652-A1 MODIFIED PHENYLPHTHALIMIDE AND PHARMACEUTICAL COMPOSITION HAVING SAME AS ACTIVE INGREDIENT Keio University (JP) 2019-08-28 EP claimed
WO-2016042349-A1 NEW AGENTS FOR TREATING NEUROGENIC INFLAMMATION AND NEUROPATHIC HYPERALGESIA RELATED DISORDERS PÉCSI TUDOMÁNYEGYETEM (HU) 2016-03-24 WO claimed
WO-2014195152-A1 IMPROVED HYBRID SEED PRODUCTION METHOD BAYER CROPSCIENCE NV (BE) 2014-12-11 WO claimed
US-20100069247-A1 HERBICIDE COMPOSITION KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-03-18 US claimed
CN-101636084-A Herbicidal composition KUMIAI CHEMICAL INDUSTRY CO 2010-01-27 CN claimed
EP-2135508-A1 HERBICIDE COMPOSITION Kumiai Chemical Industry CO., LTD. (JP) 2009-12-23 EP claimed
WO-2008088336-A1 COATED ARTICLES OF MANUFACTURE MADE OF HIGH Tg POLYMER BLENDS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-24 WO claimed
EP-1521588-A2 USE OF ALANYL-AMINOPEPTIDASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS Institut für Medizintechnologie Magdeburg GmbH IMTM. (DE) 2005-04-13 EP claimed
WO-2004004750-A2 USE OF ALANYL-AMINOPEPTIDASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS INSTITUT FÜR MEDIZINTECHNOLOGIE MAGDEBURG GMBH IMTM (DE) 2004-01-15 WO claimed
WO-1996015667-A2 ANTIDOTE COMPOSITION AND METHOD FOR USE OF THE COMPOSITION Nitrokémia Rt. (HU) 1996-05-30 WO claimed
US-3987056-A DISPROPORTIONATION OF N-ARYL-1,2,3,6-TETRAHYDROPHTHALIMIDES PHILLIPS PETROLEUM COMPANY (US) 1976-10-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315775-A1 MODIFIED PHENYLPHTHALIMIDE AND PHARMACEUTICAL COMPOSITION HAVING SAME AS ACTIVE INGREDIENT HNRNPL, HNRNPLL, CCNL2 GSK3B 3828/4885CASP3 2454/4885CASP2 3315/4885
US-20100069247-A1 HERBICIDE COMPOSITION ABCC5, DDT, DRD5 GSK3B 2162/4885CASP3 841/4885CASP2 1114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.