SCHEMBL28099640

SCHEMBL28099640

C=CC(=O)c1nc2ccccc2cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 5/20 0.44
HPGD P15428 4/20 0.44
MAPT P10636 4/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MEN1 O00255 2/20 0.44
MAPK1 P28482 2/20 0.44
EGFR P00533 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
JAK1 P23458 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PDE10A Q9Y233 1/20 0.44
GAA P10253 2/20 0.42
STAT3 P40763 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18781432 0.82 TDP1 (0.47) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL27822691 0.80 TDP1 (0.52) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL2329568 0.80 ALDH1A1 (0.59) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL27830676 0.79 PPARA (0.51) ALDH1A1MAPTKMT2ASMN1; SMN2MAPK1
SCHEMBL27830675 0.79 PPARA (0.51) ALDH1A1MAPTKMT2ASMN1; SMN2MAPK1
SCHEMBL16992688 0.78 IKBKB (0.53) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL11090058 0.77 KDM4E (0.49) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL11096992 0.77 TDP1 (0.49) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL13629231 0.76 TDP1 (0.52) TDP1ALDH1A1KDM4EHPGDMAPT
SCHEMBL8905796 0.75 TDP1 (0.47) TDP1ALDH1A1KDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104830243-B Double-sided adhesive sheet and its manufacturing method 日东电工株式会社 2019-06-14 CN disclosed
CN-105263995-B Surface modification method and surface modification body 住友橡胶工业株式会社 2019-05-28 CN disclosed
CN-109111813-A Antifogging agent composition and antifogging article having antifogging coating film 日油株式会社 2019-01-01 CN disclosed
CN-105073938-B Electrically peelable adhesive composition, electrically peelable adhesive sheet, and method for using electrically peelable adhesive sheet 琳得科株式会社 2017-11-28 CN disclosed
CN-105143385-B The application method of electric Stripping adhesive compositeon, electric fissility bonding sheet and electric fissility bonding sheet 琳得科株式会社 2017-09-29 CN disclosed
CN-106009938-A Composition set, shaped article production method, and shaped article 精工爱普生株式会社 2016-10-12 CN disclosed