Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27822691 | 0.81 | TDP1 (0.52) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL18463861 | 0.81 | ALDH1A1 (0.56) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL18781432 | 0.81 | TDP1 (0.47) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL2329568 | 0.78 | ALDH1A1 (0.59) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL16992688 | 0.76 | IKBKB (0.53) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL28099640 | 0.76 | TDP1 (0.46) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL14541187 | 0.76 | HTR3A (0.42) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL11096992 | 0.75 | TDP1 (0.49) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL8905796 | 0.74 | TDP1 (0.47) | TDP1PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL264132 | 0.74 | TDP1 (0.49) | TDP1ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380577-B1 | Thiazoline acid derivatives | UNIV FLORIDA (US) | 2009-11-18 | — | — | EP | disclosed |