Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953014 | 0.81 | HDAC3 (0.71) | F10MEN1KMT2ANPC1HDAC1 | |
| SCHEMBL4926542 | 0.80 | HDAC1 (0.73) | HDAC1HDAC2PDCD1CD274 | |
| SCHEMBL1110180 | 0.79 | MDM4 (0.73) | F10MEN1KMT2ANPC1HDAC1 | |
| SCHEMBL1664024 | 0.79 | MEN1 (0.59) | F10MEN1KMT2ANPC1HDAC1 | |
| SCHEMBL16317646 | 0.77 | KCNMA1 (0.76) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL3793263 | 0.77 | KCNMA1 (0.76) | MEN1KMT2ANPC1MAPT | |
| SCHEMBL4004339 | 0.77 | KCNK3 (0.76) | MEN1KMT2ANPC1PLAU | |
| SCHEMBL7409499 | 0.77 | MEN1 (0.61) | F10MEN1KMT2ANPC1HDAC1 | |
| N-Phenylbenzamide SCHEMBL18889922 | 0.77 | PTPN1 (0.70) | MEN1KMT2ANPC1PLAUHDAC1 | |
| SCHEMBL3902965 | 0.77 | KMT2A (0.72) | MEN1KMT2ANPC1PLAUMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985276-A | 3,4-dibenzamido benzamide derivative, preparation method and application thereof | 南京中瑞药业有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-105985276-A | 3,4-dibenzamido benzamide derivative, preparation method and application thereof | 南京中瑞药业有限公司 | 2016-10-05 | — | — | CN | disclosed |