Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28099743

CCC(=O)C(C)(O)C(=O)O.S

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.43
FFAR3 O14843 1/20 0.38
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
TET2 Q6N021 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14370458 0.97 ALDH1A1 (0.45) ALDH1A1TSHRFFAR3HMGCRCHRM1
Hydrogen Sulfide SCHEMBL28112419 0.80 HDAC3 (0.42) ALDH1A1TSHRFFAR3HMGCRCHRM1
SCHEMBL5270259 0.77 HDAC3 (0.43) ALDH1A1TSHRFFAR3HMGCRCHRM1
Hydrogen Sulfide SCHEMBL28099748 0.77 FAAH (0.43) ALDH1A1TSHRTDP1
SCHEMBL2864735 0.76 TDP1 (0.40) ALDH1A1TSHRFFAR3HMGCRCHRM1
SCHEMBL5825706 0.74 TSHR (0.43) ALDH1A1TSHRHMGCRCHRM1TBXA2R
SCHEMBL9616754 0.74 ALDH1A1 (0.43) ALDH1A1TSHRHMGCRCHRM1TBXA2R
SCHEMBL2311220 0.74 TSHR (0.43) ALDH1A1TSHRHMGCRCHRM1TBXA2R
SCHEMBL27492133 0.73 FAAH (0.45) ALDH1A1TSHRTDP1
SCHEMBL567250 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106172876-A For giving powdered oil compositions and the adding method thereof of breast local flavor 长谷川香料株式会社 2016-12-07 CN disclosed
CN-104093695-B Capric acid derivatives and perfume compositions 长谷川香料株式会社 2016-08-31 CN disclosed