Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451795 | 1.00 | TSHR (0.57) | TSHRLOXL2CYP4F2CYP4A11HCRTR1 | |
| SCHEMBL29732178 | 1.00 | TSHR (0.57) | TSHRLOXL2CYP4F2CYP4A11HCRTR1 | |
| Hydrochloric Acid SCHEMBL11231916 | 0.98 | TSHR (0.55) | TSHRLOXL2CYP4F2CYP4A11HCRTR1 | |
| SCHEMBL7358622 | 0.93 | KDM4E (0.57) | TSHRLOXL2CYP4F2CYP4A11HCRTR1 | |
| SCHEMBL34953 | 0.85 | TSHR (0.70) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL13949640 | 0.85 | HDAC1 (0.54) | TSHRRAB9APOLBALDH1A1NPC1 | |
| SCHEMBL11264665 | 0.83 | HDAC1 (0.42) | LOXL2CYP4F2CYP4A11HCRTR1HCRTR2 | |
| SCHEMBL8054504 | 0.83 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| Methyl Alcohol SCHEMBL28469619 | 0.83 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL29966404 | 0.83 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178092-B | Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof | 苏州大学 | 2024-11-22 | — | — | CN | claimed |
| CN-114920736-B | Quinoline ring-containing 1,2, 4-oxadiazole substituted benzamide compound and preparation method and application thereof | 浙江工业大学 | 2024-01-30 | — | — | CN | claimed |
| CN-114656461-B | Quinoline ring-containing 1,2, 4-oxadiazole substituted benzamide compound and synthetic method and application thereof | 浙江工业大学 | 2024-01-30 | — | — | CN | claimed |
| CN-116178092-A | Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof | 苏州大学 | 2023-05-30 | — | — | CN | claimed |
| CN-112939829-B | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2023-02-21 | — | — | CN | claimed |
| CN-115286622-A | Quinoline ring-containing 1,2, 4-oxadiazole substituted benzamide compound and preparation method and application thereof | 浙江工业大学 | 2022-11-04 | — | — | CN | claimed |
| CN-115260175-A | 5- (pyrazole-5-yl) -1,2,4-oxadiazole substituted benzamide compound and preparation method and application thereof | 浙江工业大学 | 2022-11-01 | — | — | CN | claimed |
| CN-114920736-A | Quinoline ring-containing 1,2, 4-oxadiazole-substituted benzamide compound and preparation method and application thereof | 浙江工业大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114920734-A | 5- (pyrazole-5-yl) -1,2, 4-oxadiazole substituted benzamide compounds and preparation method and application thereof | 浙江工业大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114656461-A | Quinoline ring-containing 1,2, 4-oxadiazole-substituted benzamide compound and synthetic method and application thereof | 浙江工业大学 | 2022-06-24 | — | — | CN | claimed |
| CN-110407710-B | Triphenylamine derivative pure organic room temperature phosphorescent material and preparation method thereof | 香港科技大学深圳研究院 | 2022-05-06 | — | — | CN | claimed |
| CN-113731506-A | Method for assisting palladium-catalyzed C-H arylation reaction of aliphatic aldehyde by calix [4] arene amide compound | 常州大学 | 2021-12-03 | — | — | CN | claimed |
| CN-112939829-A | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-112724177-A | Ring metal iridium complex and preparation method and application thereof | 四川大学 | 2021-04-30 | — | — | CN | claimed |
| CN-109400635-A | A kind of asymmetric double degree of functionality carborane derivative and preparation method and application | 北京航空航天大学 | 2019-03-01 | — | — | CN | claimed |
| US-4328162-A | Process for preparing 9,11-unsaturated steroidal compound from the corresponding saturated steroidal compound | EASTMAN KODAK COMPANY (US) | 1982-05-04 | — | — | US | claimed |
| CN-122071464-A | Heterocyclic compound, pharmaceutical composition thereof and application thereof | 上海璎黎药业有限公司 | 2026-05-22 | — | — | CN | disclosed |
| US-12629374-B2 | Antimalarial agents | MERCK SHARP & DOHME LLC (US) | 2026-05-19 | — | — | US | disclosed |
| US-4214004-A | MITICIDES | FMC CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| WO-1980001163-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC CORP (US) | 1980-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629374-B2 | Antimalarial agents | CLIC1, CYC1, HCCS | TSHR 2452/4885LOXL2 2918/4885CYP4F2 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.