Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264669 | 0.94 | LMNA (0.48) | HDAC1HDAC2GRM5F2MTOR | |
| Biphenyl SCHEMBL7934686 | 0.91 | KMO (0.47) | F2MTORLMNAATMTDP1 | |
| SCHEMBL28379117 | 0.90 | HDAC1 (0.40) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL6422675 | 0.85 | MTOR (0.43) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL6971830 | 0.83 | HDAC1 (0.41) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL29732178 | 0.83 | TSHR (0.57) | HDAC1HDAC2GRM5HCRTR1HCRTR2 | |
| SCHEMBL28766468 | 0.83 | IDO1 (0.41) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL14022964 | 0.83 | HDAC1 (0.41) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL7451795 | 0.83 | TSHR (0.57) | HDAC1HDAC2GRM5HCRTR1HCRTR2 | |
| SCHEMBL281 | 0.83 | TSHR (0.57) | HDAC1HDAC2GRM5HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323512-A | Process for the preparation of steroidal 17α-arylcarboxylates | SCHERING CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| US-4260464-A | Process for the preparation of 17α-(3-iodobenzoyloxy)-9α-chloro-4-pregnene-3,20-diones and their D-homo homologs | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |