Methane

Methane

SCHEMBL28100002

C.NC(N)C(O)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 1/20 0.48
KCNN4 O15554 1/20 0.42
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KCNA5 P22460 3/20 0.40
MEN1 O00255 1/20 0.39
TTR P02766 1/20 0.39
KMT2A Q03164 1/20 0.39
KIF11 P52732 3/20 0.35
CYP1A2 P05177 2/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2C P18825 1/20 0.34
CYP2C9 P11712 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28014598 0.98 KDM4E (0.50) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL7207713 0.84 ALDH1A1 (0.47) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL8579927 0.79 ALDH1A1 (0.44) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL7763320 0.76 CYP2D6 (0.50) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL8579679 0.74 ALDH1A1 (0.47) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL301345 0.74 ALDH1A1 (0.57) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL6021075 0.74 ALDH1A1 (0.57) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL7491387 0.73 CYP2D6 (0.52) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL1153634 0.73 CYP2D6 (0.52) KDM4ELMNAMAPK1KCNN4CYP2C19
SCHEMBL295338 0.73 CYP2D6 (0.52) KDM4ELMNAMAPK1KCNN4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029744-B Polyimide resin, resin combination and stacked film using it 东丽株式会社 2018-08-28 CN disclosed
CN-106029744-A POLYIMIDE RESIN, RESIN COMPOSITION USING SAME, AND LAMINATED FILM 东丽株式会社 2016-10-12 CN disclosed