Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301345 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL25608886 | 0.89 | CYP17A1 (0.54) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL1819046 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL6470482 | 0.86 | CYP2C19 (0.55) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL7763320 | 0.85 | CYP2D6 (0.50) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL27480267 | 0.85 | CYP2C19 (0.50) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL8579679 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL7207713 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL5696425 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL17231876 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113897414-B | Trace nucleic acid library construction method | 湖南大地同年生物科技有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-113801125-B | Preparation method of cyclic anhydride | 安徽泰格维生素实业有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-113897414-A | Trace nucleic acid library construction method | 湖南大地同年生物科技有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113801125-A | Preparation method of cyclic anhydride | 安徽泰格维生素实业有限公司 | 2021-12-17 | — | — | CN | claimed |
| US-20060074248-A1 | Process for the stereoselective synthesis of lactones | DSM IP ASSETS B.V. (NL) | 2006-04-06 | — | — | US | claimed |
| EP-1618110-A2 | A PROCESS FOR THE STEREOSELECTIVE SYNTHESIS OF LACTONES | DSM IP Assets B.V. (NL) | 2006-01-25 | — | — | EP | claimed |
| WO-2004094367-A2 | A PROCESS FOR THE STEREOSELECTIVE SYNTHESIS OF LACTONES | DSM IP ASSETS B.V. (NL) | 2004-11-04 | — | — | WO | claimed |
| US-6166260-A | Tandem reduction and host-guest complexation | ZEELAND CHEMICALS, INC. (US) | 2000-12-26 | — | — | US | claimed |
| EP-0161580-B1 | PROCESS FOR THE PREPARATION OF A LACTON | F. HOFFMANN-LA ROCHE AG (CH) | 1990-11-07 | — | — | EP | claimed |
| EP-0161580-A2 | Process for the preparation of a lacton | F. HOFFMANN-LA ROCHE AG (CH) | 1985-11-21 | — | — | EP | claimed |
| CN-113897414-B | Trace nucleic acid library construction method | 湖南大地同年生物科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-114560865-B | Continuous flow synthesis method of (3 aS,6 aR) -lactone | 复旦大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-113801125-B | Preparation method of cyclic anhydride | 安徽泰格维生素实业有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-113549084-B | Method for stereoselectively synthesizing chiral lactone | 杭州科兴生物化工有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-113121549-B | Method for stereoselectively synthesizing chiral lactone, chiral compound and application thereof | 江西天新药业股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| US-6166260-A | Tandem reduction and host-guest complexation | ZEELAND CHEMICALS, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| US-6093826-A | Process for the preparation of C(5)-substituted 1,2-dihydro-5H-chromeno[3,4-f] quinolines | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0161580-B1 | PROCESS FOR THE PREPARATION OF A LACTON | F. HOFFMANN-LA ROCHE AG (CH) | 1990-11-07 | — | — | EP | disclosed |
| US-4687859-A | CHEMICAL INTERMEDIATE FOR BIOTIN | HOFFMANN-LA ROCHE INC. (US) | 1987-08-18 | — | — | US | disclosed |
| US-4628120-A | REARRANGEMENTS USING ORGANOALUMINUM COMPOUNDS | TOYO STAUFFER CHEMICAL CO., LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074248-A1 | Process for the stereoselective synthesis of lactones | COASY, ADSL, ALAD | ALDH1A1 350/4885CYP2D6 1056/4885CYP2C19 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.