Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412073 | 0.84 | GAA (0.58) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL12850382 | 0.84 | GAA (0.58) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL5177083 | 0.84 | GAA (0.58) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL5177067 | 0.83 | GAA (0.57) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL5177074 | 0.83 | GAA (0.57) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL1549839 | 0.82 | NPC1 (0.63) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL29473469 | 0.82 | NPC1 (0.63) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL23507038 | 0.80 | MAPT (0.50) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL29366694 | 0.79 | GAA (0.56) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL224821 | 0.79 | GAA (0.56) | GAAMAPTKMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459377-B | Benzo [B] [Isosorbide-5-Nitrae] oxazine derivatives as calcium-sensing receptor modulating agent | 鲁平有限公司 | 2016-09-07 | — | — | CN | disclosed |