Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177083 | 1.00 | GAA (0.58) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL15412073 | 1.00 | GAA (0.58) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL5177067 | 0.85 | GAA (0.57) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL5177074 | 0.85 | GAA (0.57) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL26659445 | 0.84 | KDM4E (0.50) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL26659382 | 0.84 | KDM4E (0.50) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL28100110 | 0.84 | GAA (0.59) | GAAMAPTKDM4EKMT2ATDP1 | |
| SCHEMBL5174596 | 0.83 | RAB9A (0.65) | GAAMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL5691808 | 0.80 | CA1 (0.52) | KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5177152 | 0.79 | PARP1 (0.65) | GAAMAPTKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365730-A1 | HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF | KANEKA CORPORATION (JP) | 2023-11-16 | — | — | US | disclosed |
| EP-2686306-B1 | BENZO[B][1,4]OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN ATLANTIS HOLDINGS SA (CH) | 2017-01-04 | — | — | EP | disclosed |
| US-9464063-B2 | Benzo [B] [1,4] oxazin derivatives as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9464063-B2 | Benzo [B] [1,4] oxazin derivatives as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-10-11 | — | — | US | disclosed |
| US-20140018358-A1 | BENZO [B] [1,4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2014-01-16 | — | — | US | disclosed |
| US-20140018358-A1 | BENZO [B] [1,4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2014-01-16 | — | — | US | disclosed |
| WO-2012127388-A1 | BENZO [B] [1, 4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2012-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365730-A1 | HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF | KDM5C, DHX15, KDM5A | GAA 1500/4885MAPT 969/4885KDM4E 135/4885 |
| US-20140018358-A1 | BENZO [B] [1,4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | CASR, RYR1, RYR2 | GAA 1225/4885MAPT 2509/4885KDM4E 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.