Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28100589 | 0.89 | MAPT (0.46) | ALDH1A1LMNASMN1; SMN2MAPTSOS1 | |
| SCHEMBL28834566 | 0.78 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL28100418 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL23363999 | 0.74 | PDE4A (0.53) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL30791400 | 0.74 | PDE4A (0.53) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL16832763 | 0.73 | LMNA (0.66) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL1761213 | 0.73 | ALDH1A1 (0.45) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL13186671 | 0.71 | MEN1 (0.80) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL9917428 | 0.68 | HDAC3 (0.42) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL1578345 | 0.67 | MAOB (0.49) | LMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | disclosed |