Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21543374 | 0.79 | PDK2 (0.43) | PDK2HDAC4L3MBTL1 | |
| SCHEMBL19205328 | 0.77 | PDK2 (0.46) | PDK2TDP1HDAC4L3MBTL1 | |
| SCHEMBL18797720 | 0.76 | RORC (0.47) | PDK2TDP1HDAC4L3MBTL1RORC | |
| SCHEMBL21543242 | 0.75 | PDK2 (0.44) | PDK2HDAC4OPRM1TSHROPRK1 | |
| SCHEMBL20455827 | 0.75 | PDK2 (0.43) | PDK2HDAC4 | |
| SCHEMBL19205349 | 0.75 | PDK2 (0.47) | PDK2TDP1OPRM1TSHROPRD1 | |
| SCHEMBL19291084 | 0.75 | PDK2 (0.47) | PDK2HDAC4 | |
| SCHEMBL23206456 | 0.73 | ALDH1A1 (0.42) | PDK2TSHRL3MBTL1 | |
| SCHEMBL18797724 | 0.72 | PDK2 (0.42) | PDK2HDAC4RORC | |
| SCHEMBL19743353 | 0.71 | PDK2 (0.43) | PDK2TDP1ACHETSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443080-B | There is the sulfonamide compounds of TRPM8 antagonistic activity | 田边三菱制药株式会社 | 2016-10-12 | — | — | CN | disclosed |