Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777889 | 0.77 | ELANE (0.53) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL28145983 | 0.77 | ELANE (0.53) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL29502090 | 0.77 | ELANE (0.53) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL29794152 | 0.77 | ELANE (0.53) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL31196219 | 0.77 | ELANE (0.49) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL30201876 | 0.74 | BCAT1 (0.66) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL23994382 | 0.73 | ELANE (0.46) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL15759319 | 0.72 | ELANE (0.44) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL2723844 | 0.72 | ELANE (0.51) | ELANEF2PLAUCTRB1BCAT1 | |
| SCHEMBL3532632 | 0.71 | GPR3 (0.36) | ALDH1A1KDM4EPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619698-B | Pyrrolidin derivatives and the purposes as complement pathway regulator thereof | 诺华股份有限公司 | 2016-08-31 | — | — | CN | disclosed |