Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | LTA4H | P09960 | 6/20 | 0.70 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | HTR1D | P28221 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | HTR1B | P28222 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406721 | 0.89 | TRPM8 (0.77) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL29007183 | 0.89 | TRPM8 (0.76) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL29617411 | 0.89 | TRPM8 (0.76) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL24183187 | 0.87 | TRPM8 (0.74) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL27691651 | 0.86 | MTNR1A (0.65) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL2007192 | 0.86 | TRPM8 (0.72) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL6987351 | 0.84 | SLC6A4 (0.77) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL6388022 | 0.84 | POLB (0.78) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL6988545 | 0.84 | HTR1D (0.78) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| 5-Benzyloxytryptamine SCHEMBL29785061 | 0.84 | TRPM8 (1.00) | TRPM8KDM4EMAPTLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997172-A | Antitumor compounds | 中国人民解放军总医院 | 2018-12-14 | — | — | CN | disclosed |
| CN-105916840-A | Indole compound | 安斯泰来制药株式会社 | 2016-08-31 | — | — | CN | disclosed |