Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269462 | 0.83 | APLNR (0.57) | APLNR | |
| SCHEMBL1863100 | 0.80 | APLNR (0.46) | APLNR | |
| SCHEMBL28318062 | 0.78 | — | — | |
| SCHEMBL28100920 | 0.76 | — | — | |
| SCHEMBL27908928 | 0.72 | GABRA5 (0.35) | — | |
| Alcohol SCHEMBL27824847 | 0.69 | — | — | |
| SCHEMBL30154499 | 0.66 | TDP1 (0.30) | — | |
| SCHEMBL9293 | 0.66 | — | — | |
| SCHEMBL52124 | 0.65 | APLNR (0.34) | APLNR | |
| SCHEMBL30843655 | 0.65 | APLNR (0.39) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916855-B | Substituted 4, 5, 6, 7-tetrahydropyrazolo [1,5-a ] pyrazine derivatives as casein kinase 1D/E inhibitors | 百时美施贵宝公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-105916855-A | Substituted 4,5,6, 7-tetrahydropyrazolo [1,5-a ] pyrazine derivatives as casein kinase 1D/E inhibitors | 百时美施贵宝公司 | 2016-08-31 | — | — | CN | disclosed |