Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15009561 | 0.90 | AHR (0.47) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL3857441 | 0.80 | MEN1 (0.46) | TDP1TSHRSMN1; SMN2GPR35ALDH1A1 | |
| SCHEMBL18489004 | 0.79 | ALDH1A1 (0.52) | TDP1SMN1; SMN2GPR35HSD17B10ALDH1A1 | |
| SCHEMBL4998134 | 0.79 | TDP1 (0.40) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL2934863 | 0.76 | TDP1 (0.64) | TDP1SMN1; SMN2GPR35HSD17B10ALDH1A1 | |
| SCHEMBL2043864 | 0.75 | ALOX5 (0.50) | TDP1SMN1; SMN2GPR35HSD17B10ALDH1A1 | |
| SCHEMBL18936147 | 0.74 | TDP1 (0.47) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL2927803 | 0.74 | ALDH1A1 (0.46) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL4486055 | 0.74 | CHRNB4 (0.47) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL2962443 | 0.73 | MAPT (0.47) | TDP1TSHRSMN1; SMN2GPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106119220-B | A kind of Kidney bean epoxide hydrolase mutant of catalytic activity and the raising of mapping regression nature | 江南大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-106119220-A | A kind of Kidney bean Epoxide hydrolase mutant being catalyzed activity and the raising of mapping regression nature | 江南大学 | 2016-11-16 | — | — | CN | disclosed |