Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 2/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267696 | 0.92 | KDM1A (0.50) | FABP7FABP5MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL15248901 | 0.92 | KDM1A (0.50) | FABP7FABP5MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL15687569 | 0.89 | MAOB (0.52) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL23518769 | 0.84 | FABP7 (0.63) | FABP7FABP5MAPK1TDP1ALDH1A1 | |
| SCHEMBL1838935 | 0.83 | ALDH1A1 (0.55) | FABP7FABP5MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL1838938 | 0.83 | ALDH1A1 (0.55) | FABP7FABP5MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL4135351 | 0.82 | MAPT (0.62) | MAPK1TDP1SMN1; SMN2ALDH1A1HDAC4 | |
| SCHEMBL928888 | 0.82 | MAPT (0.62) | MAPK1TDP1SMN1; SMN2ALDH1A1HDAC4 | |
| SCHEMBL4129635 | 0.82 | MAPT (0.62) | MAPK1TDP1SMN1; SMN2ALDH1A1HDAC4 | |
| SCHEMBL12706756 | 0.82 | MAPT (0.62) | MAPK1TDP1SMN1; SMN2ALDH1A1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103826661-B | Novel binding agent-drug conjugates (ADCs) and uses thereof | 西雅图基因公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-106117312-A | New bonding agent drug conjugate (ADC) and application thereof | 西雅图基因公司 | 2016-11-16 | — | — | CN | disclosed |